Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway.
Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein . Seems to be localized intracellularly to the trans Golgi network. .
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.
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