RNA-binding protein involved in pre-mRNA splicing . Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome . Involved in regulating splice site selection . Binds preferentially RNA with A/C rich sequences and poly-C stretches .
Nucleus . Cytoplasm .
Ubiquitous. Expressed at high level in skeletal muscle, kidney, heart, brain and liver.
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