Functions as a transcriptional repressor . May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth . May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). ; (Microbial infection) Plays a role in hepatitis delta virus (HDV) genomic replication.
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, adherens junction .
Widely expressed including liver.
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