As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death.
Cytoplasm, cytosol . Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side . May cycle on and off membranes.
Expressed in various tumor cell lines including Jurkat, Hep-G2 and HeLa.