Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. ; (Microbial infection) In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.
Nucleus, nuclear pore complex . Nucleus membrane ; Peripheral membrane protein; Cytoplasmic side . Excluded from the nucleolus. .
Ubiquitously expressed.
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