transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
Nucleus . Nucleus, nucleoplasm . Chromosome, telomere . Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.; [Isoform 5]: Cytoplasm .
Expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta. ; [Isoform 4]: Strongly expressed in skeletal muscle. Also expressed at lower levels in heart and lung.