RNA-binding protein that mediates pre-mRNA alternative splicing regulation.
Nucleus . Nucleus speckle . Colocalizes with splicing factors SRSF1 and SRSF2 in speckles.
Expressed in dendritic cells, T-cells, B-cells and natural killer cells. Expressed in secondary lymphoid organs such as spleen and mesenteric, axillary and brachial lymph nodes.