Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
Membrane ; Single-pass membrane protein . Cytoplasm . Slightly concentrates in the perinuclear region (PubMed:12118381). .
Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level).
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