Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.
Cytoplasm, cytoskeleton . Cell junction . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Detected in the cytoplasm of actively dividing cells.
Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung.
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