Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Mitochondrion .
Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
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