Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.
Cytoplasm, cytosol .
Ubiquitous (PubMed:9099727, PubMed:31187503). Highly expressed in testis (PubMed:9099727). ; [Isoform 3]: In adult testis and spermatozoa.