Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi . Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase . ; (Microbial infection) Plays an essential role in Aichi virus RNA replication by recruiting PI4KB at the viral replication sites.
Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Mitochondrion . Also mitochondrial (via its interaction with PBR). .
Ubiquitous, with highest expression in testis and ovary.
下载说明书
