AP-1 (phospho Ser63) Polyclonal Antibody

  • Catalog Number:
    RA11950
  • Size:
    50μL 100μL 200μL
  • Price:
    1500 / 2800 / 4680 RMB(含税报价)
  • Form:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Reactivity:
    Human ; Mouse ; Rat
  • Application:
    WB IHC ICC/IF ELISA
功能
细胞定位
组织表达
function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.,PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.,
Nucleus.
Expressed in the developing and adult prostate and prostate cancer cells.