PKD1 (phospho Ser910) Polyclonal Antibody

  • Catalog Number:
    RA12267
  • Size:
    50μL 100μL 200μL
  • Price:
    1500 / 2800 / 4680 RMB(含税报价)
  • Form:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Reactivity:
    Human ; Mouse ; Rat
  • Application:
    WB IHC ICC/IF ELISA
功能
细胞定位
组织表达
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by diacylglycerol and phorbol esters.,function:Calcium-independent, phospholipid-dependent, serine- and threonine-specific kinase involved in resistance to oxidative stress.,PTM:Phosphorylation of Ser-738 and/or Ser-742 in activated PKD is mediated by transphosphorylation (By similarity). Phosphorylation of Tyr-463 mediated by the Src/Abl pathway in response to oxidative stress activates the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,subunit:Interacts (via N-terminus) with ADAP1/CENTA1. Interacts with Src.,
Cytoplasm . Cell membrane . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation.
Placenta,Testis,