Splicing factor 1 (phospho Ser82) Polyclonal Antibody

  • Catalog Number:
    RA12826
  • Size:
    50μL 100μL 200μL
  • Price:
    1500 / 2800 / 4680 RMB(含税报价)
  • Form:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Reactivity:
    Human ; Mouse ; Monkey
  • Application:
    WB IHC ICC/IF ELISA
功能
细胞定位
组织表达
alternative products:Additional isoforms seem to exist,function:Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.,PTM:Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.,similarity:Belongs to the BBP/SF1 family.,similarity:Contains 1 CCHC-type zinc finger.,similarity:Contains 1 KH domain.,subunit:Binds U2AF2. Interacts with U1 snRNA. Binds EWSR1, FUS and TAF15.,tissue specificity:Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart.,
Nucleus.
Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart.