transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
Nucleus . Cytoplasm . Present in the nucleus and cytoplasm, but shows increased nuclear translocation after activation of T-cells. .
Expressed at highest levels in lung, and at lower levels in placenta, liver, kidney, spleen, and peripheral blood. Detected in SW480 colorectal cancer cell line and several hematopoietic tumor cell lines, including Raji Burkitt's lymphoma. Strongly expressed in mature B- and T-lymphocytes. Also expressed in moderate levels in lymph node and appendix and at low levels in thymus and bone marrow (PubMed:10777209).
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