ABCC13 Polyclonal Antibody

alternative products:Experimental confirmation may be lacking for some isoforms,caution:Contains sequences related to the ABC transporters of subfamily C, but lacks Walker A, Walker B, and signature C motifs, indicating that it is a nonfunctional ABC transporter. Translation of the cDNA in a different reading frame predicts a 93 amino acid peptide with signature C and Walker B motifs, but no Walker A motif.,induction:Down-regulated by cell differentiation in certain leukemia cells.,similarity:Belongs to the binding-protein-dependent transport system permease family.,similarity:Contains 1 ABC transmembrane type-1 domain.,tissue specificity:Highest expression in fetal liver and fetal spleen. In the adult, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood leukocytes.,