function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated. Phosphorylation on Thr-556 occurs specifically during mitosis.,similarity:Belongs to the APC8/CDC23 family.,similarity:Contains 9 TPR repeats.,subunit:The APC/C is composed of at least 11 subunits.,
intracellular,nucleoplasm,anaphase-promoting complex,cytosol,
Bone marrow,Brain,Duodenum,Epithelium,Pancreas,Placenta,
下载说明书
