catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.,induction:By 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).,online information:CYP1A1 alleles,online information:CYP1A1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Lung, lymphocytes and placenta.,
Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion inner membrane ; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein . Cytoplasm .
Lung, lymphocytes and placenta.
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