catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.,online information:CYP2J2 alleles,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.,
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.
Highly expressed in heart, present at lower levels in liver, kidney and skeletal muscle (at protein level).
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