function:Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production.,similarity:Belongs to the alpha-defensin family.,subunit:Homodimer.,
Secreted . Cytoplasmic vesicle, secretory vesicle . Stored as mature peptide in neutrophil granules. .
Expressed in neutrophils (at protein level) (PubMed:2843187, PubMed:2500436, PubMed:2501794). Expressed in bone marrow (PubMed:8469233).
下载说明书
