catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,enzyme regulation:Stimulated by phosphatidylserine.,function:Exhibits high phosphorylation activity for long-chain diacylglycerols.,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 2 EF-hand domains.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,
Cell junction, synapse, postsynaptic cell membrane ; Peripheral membrane protein . Cell membrane ; Peripheral membrane protein . Cytoplasm . Translocation to the plasma membrane is induced by phorbol esters. .; [Isoform 2]: Cytoplasm .
[Isoform 1]: Specifically expressed in brain but also detected in uterus (PubMed:11719522). In adult brain, expressed in the amygdala, caudate nucleus, and hippocampus (PubMed:11719522). ; [Isoform 2]: More ubiquitously expressed but at lower level compared to isoform 1.
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