catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,function:May play a role in allowing polymerase epsilon to carry out its replication and/or repair function.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Consists of four subunits: POLE1, POLE2, POLE3 and POLE4. Interacts with POLE3. When bound to POLE3, it can associate with polymerase epsilon p261 and p59 and form a complex.,
Nucleus .
Cervix carcinoma,Skin,
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