function:Inhibits glucokinase by forming an inactive complex with this enzyme.,similarity:Belongs to the GCKR family.,similarity:Contains 1 SIS domain.,tissue specificity:Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.,
Cytoplasm . Nucleus . Mitochondrion . Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus. .
Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.
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