function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.,online information:ICAM-2,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,
Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Co-localizes with RDX, EZR and MSN in microvilli. .
Aorta endothelial cell,Blood,Brain,Endothelial cell,Plasma,Spleen,
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