domain:The IMD domain is predicted to have a helical structure. It may induce actin bundling and filopodia formation.,function:May function as adapter protein (Potential). Involved in the formation of clusters of actin bundles.,PTM:Phosphorylated on tyrosine in response to insulin.,similarity:Contains 1 IMD (IRSp53/MIM homology) domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with RAC1. Binds to F-actin.,
Cytoplasm, cytoskeleton . Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
Adrenal gland,Epithelium,Lung,Placenta,
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