similarity:Belongs to the JTB family.,tissue specificity:Expressed in all normal human tissues studied but overexpressed in most of their malignant counterparts.,
Membrane ; Single-pass type I membrane protein . Mitochondrion . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.