release of cytochrome c from mitochondria, protein targeting, protein targeting to mitochondrion, mitochondrial transport, intracellular protein transport, apoptosis, induction of apoptosis, mitochondrion organization, mitochondrial membrane organization, protein localization, cell death, induction of apoptosis by extracellular signals, activation of pro-apoptotic gene products, apoptotic mitochondrial changes, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, protein transport, membrane organization, death,protein import, protein localization in organelle, cellular protein localization, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, establishment of protein localization, regulation of mitochondrial membrane permeability, intracellular transport, neuron apoptosis,protein localization in mitochondrion, cellular macromolecule localization,
Cytoplasm . Mitochondrion membrane . Mitochondrion outer membrane . When uncleaved, it is predominantly cytoplasmic. .; [BH3-interacting domain death agonist p15]: Mitochondrion membrane . Translocates to mitochondria as an integral membrane protein. .; [BH3-interacting domain death agonist p13]: Mitochondrion membrane . Associated with the mitochondrial membrane. .; [Isoform 1]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 2]: Mitochondrion membrane . A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively. .
[Isoform 2]: Expressed in spleen, pancreas and placenta (at protein level). ; [Isoform 3]: Expressed in lung, pancreas and spleen (at protein level). ; [Isoform 4]: Expressed in lung and pancreas (at protein level).
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