muscle system process, cell motion, muscle contraction, cytoskeleton organization, actin filament organization, actin filament-based process, actin cytoskeleton organization, positive regulation of protein binding, regulation of protein binding, positive regulation of molecular function, actin filament bundle formation, regulation of binding, positive regulation of binding,
Cytoplasm, cytoskeleton . Cytoplasm, myofibril . Cytoplasm, cytoskeleton, stress fiber . On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). .
High-molecular-weight caldesmon (isoform 1) is predominantly expressed in smooth muscles, whereas low-molecular-weight caldesmon (isoforms 2, 3, 4 and 5) are widely distributed in non-muscle tissues and cells. Not expressed in skeletal muscle or heart.
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