developmental stage:Constitutively expressed during the cell cycle.,function:Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.,subunit:Binds to purified microtubules via its C-terminus.,
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
Amygdala,Bone marrow,Brain,
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