activation of immune response, immune response-activating cell surface receptor signaling pathway, positive regulation of immune system process, immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, cell surface receptor linked signal transduction, positive regulation of response to stimulus, positive regulation of immune response, antigen receptor-mediated signaling pathway, T cell receptor signaling pathway,
Cell membrane ; Single-pass type I membrane protein.
CD3Z is expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (PBMCs) (PubMed:11722641).
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