function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 2 IQ domains.,subunit:Binds calmodulin through its IQ motifs.,tissue specificity:Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen.,
Cytoplasm . Perikaryon . Cell projection, dendrite . Early endosome . Cytoplasm, cell cortex . Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles. .
Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen.
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