microtubule cytoskeleton organization, microtubule bundle formation, reproductive developmental process, cell motion,cytoskeleton organization, microtubule-based process, gamete generation, germ cell development, spermatogenesis,spermatid development, sperm axoneme assembly, lactation, flagellum assembly, cellular component assembly involved in morphogenesis, sexual reproduction, cell projection organization, cell projection assembly, sperm motility,mammary gland development, multicellular organism reproduction, cellular component morphogenesis, axoneme assembly, flagellar axoneme assembly, flagellum organization, male gamete generation, spermatid differentiation,reproductive process in a multicellular organism, reproductive cellular process, gland development, cell motility,localization of cell,
Cytoplasm, perinuclear region . Cell membrane ; Peripheral membrane protein . Perikaryon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Localized in the cell bodies of the pyramidal neurons and distributed along their apical dendrites. Colocalized with PSD95 in postsynaptic sites. Colocalized with CPEB3 at apical dendrites of CA1 neurons (By similarity). Colocalized with JAG1 at the cell surface. .
Expressed in brain, testis, pituitary gland, pancreas and bone marrow. Also poorly expressed in malignant astrocytomas and several neuroectodermal tumor cell lines. Weakly expressed in medulloblastoma (MB) compared with normal cerebellar tissues.
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