function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,tissue specificity:Ubiquitous. Strongly expressed in skeletal muscle and kidney.,
Golgi apparatus membrane ; Multi-pass membrane protein .
Ubiquitous. Strongly expressed in skeletal muscle and kidney.