catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.,similarity:Belongs to the 5'-nucleotidase type 3 family.,tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.,
Cytoplasm.
Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.