NUB1 Polyclonal Antibody

Catalog Number：

RA16436
Size：

40μL 100μL 200μL
Price：

960 / 2300 / 3780 RMB(含税报价)
Form：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reactivity：

Human ; Mouse ; Monkey
Application：

WB IHC ICC/IF ELISA

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功能

细胞定位

组织表达

function:Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.,induction:By beta and gamma interferons.,similarity:Contains 3 UBA domains.,subcellular location:Predominantly nuclear.,subunit:Directly interacts with NEDD8 and PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome. Isoform 1 binds to NEDD8 more efficiently than isoform 2. Interacts with AIPL1.,tissue specificity:Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.,

Nucleus . Predominantly nuclear.

Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.