catalytic activity:RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.,function:Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction.,induction:Up-regulated in cells upon senescence and terminal differentiation. Up-regulated after treatment with interferon beta (IFN-beta).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the polyribonucleotide nucleotidyltransferase family.,similarity:Contains 1 KH domain.,similarity:Contains 1 S1 motif domain.,subunit:Homotrimer (Potential). Interacts with TCL1A; the interaction has no effect on PNPT1 exonuclease activity.,
Cytoplasm . Mitochondrion matrix . Mitochondrion intermembrane space ; Peripheral membrane protein .
Cervix,Epithelium,Melanoma,Skin,Teratocarcinoma,Urinary bla
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