domain:Contains F-X-F-G repeats.,function:Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL).,similarity:Belongs to the POM121 family.,subcellular location:Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase.,
Nucleus, nuclear pore complex . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase. .
Brain,Cervix,Lymph,Skin,Teratocarcinoma,Testis,Uterus,
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