domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Brain,Hippocampus,