catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.,
Cytoplasm . Nucleus . Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
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