function:Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:In the GTP-bound form, interacts with DIAPH2 isoform 3.,tissue specificity:Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues.,
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Colocalizes with RAB5 to early endosomes (By similarity). .
Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues.