function:Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination.,similarity:Belongs to the RNA polymerase II subunit 5-mediating protein family.,subunit:Component of the URI complex that contains PFD2, POLR2E/RPB5, TIP48, TIP49 and URI. Interacts with POLR2E/RPB5 and LRPPRC.,tissue specificity:Ubiquitous.,
Nucleus. Cytoplasm. Mitochondrion. Cell projection, dendrite . Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 at mitochondrion.
Ubiquitous. Expressed in ovarian cancers (at protein level). Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells.
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