miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subcellular location:Colocalizes with S100PBP in the nucleus.,subunit:Homodimer. Interacts with S100PBP and S100Z.,tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.,
Nucleus. Cytoplasm. Cell projection, microvillus membrane. Colocalizes with S100PBP in the nucleus. Colocolizes with EZR in the microvilli in a calcium-dependent manner.
Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
下载说明书
