MAPKKK cascade, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process,intracellular signaling cascade, protein kinase cascade, phosphorylation, stress-activated protein kinase signaling pathway, cellular response to stress, stress-activated MAPK cascade,
Nucleus. Cytoplasm .
Ubiquitous; with highest level of expression in skeletal muscle. Isoform 3 is found at low levels in placenta, fetal liver, and skeletal muscle.