function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Cell membrane ; Multi-pass membrane protein . Cell projection, dendrite .
Detected in lymph nodes, thymus and spleen. Detected in activated T-cells, but not in resting T-cells.
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