disease:May be involved in forms of prostate cancers.,function:Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.,similarity:Contains 1 Rab-GAP TBC domain.,tissue specificity:Expressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers.,tissue specificity:Expressed in pancreas, thymus and testis.,
Cell membrane ; Lipid-anchor . Associated with lipid rafts.
Expressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers.
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