function:May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.,PTM:Rapidly cleaved by calpain II.,PTM:Tyrosine phosphorylated.,similarity:Contains 1 C2 tensin-type domain.,similarity:Contains 1 phosphatase tensin-type domain.,similarity:Contains 1 SH2 domain.,subunit:Binds to actin filaments and interacts with phosphotyrosine-containing proteins. Interacts with STARD8.,tissue specificity:Ubiquitous.,
Cell surface . Cell junction, focal adhesion . Cytoplasm, cytoskeleton . Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.
Ubiquitous.
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