TP53INP1 Polyclonal Antibody

Catalog Number：

RA17714
Size：

40μL 100μL 200μL
Price：

960 / 2300 / 3780 RMB(含税报价)
Form：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reactivity：

Human ; Mouse ; Rat
Application：

WB IHC ICC/IF ELISA

下载说明书

功能

细胞定位

组织表达

function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,

Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

Ubiquitously expressed.