function:Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.,miscellaneous:Inhibited by Ni(2+) ions. Fe(2+) ions do not inhibit zinc uptake.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,subcellular location:Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.,tissue specificity:Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.,
Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.
Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.
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