ovulation from ovarian follicle, epithelial cell development, epithelial cell maturation, reproductive developmental process, transcription, regulation of transcription, DNA-dependent, intracellular signaling cascade, cell-cell signaling,gamete generation, female gamete generation, sex differentiation, gonad development, female gonad development,sexual reproduction, developmental maturation, ovulation cycle process, steroid hormone receptor signaling pathway,intracellular receptor-mediated signaling pathway, ovulation, epithelial cell differentiation, mammary gland development, multicellular organism reproduction, regulation of cell proliferation, ovulation cycle, development of primary sexual characteristics, regulation of transcription, development of primary female sexual characteristics,female sex differentiation, cell maturation, rhythmic process, reproductive structure development, reproductive process in a multicellular organism, gland development, regulation of epithelial cell proliferation, progesterone receptor signaling pathway, regulation of RNA metabolic process, epithelium development,
Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.; [Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.; [Isoform 4]: Mitochondrion outer membrane .
In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region-specific responses to hormonal stimuli.
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